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Ac-DEVD-pNA
添加购物车| 名称 | Ac-DEVD-pNA |
|---|---|
| CAS No. | 189950-66-1 |
| 目录号 | ONP10922 |
| 规格 | mg/g |
| 纯度 | ≥98% |
| 价格 | 更多在线询价 |
| 贮存 | -20°C |
| 分子量 | 638.58 |
| 序列结构 | Ac-Asp-Glu-Val-Asp-PNA |
| 库存 | |
| 产品简述 | During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-pNA is a para-nitro aniline chromophore cleaved by caspases (Km = 18, 11, 32, 180, and 12 µM for caspases-1, -3, -4, -6, and -7, respectively). It is not cleaved by caspase-2.2 Cleavage is monitored colorimetrically at 405 nm. |