关注我们
Integrin-BindingSite
添加购物车| 名称 | Integrin-BindingSite |
|---|---|
| CAS No. | |
| 目录号 | ONP10804 |
| 规格 | mg/g |
| 纯度 | ≥98% |
| 价格 | 更多在线询价 |
| 贮存 | -20°C |
| 分子量 | 614.6 |
| 序列结构 | H-Gly-Arg-Gly-Asp-Asn-Pro-OH |
| 库存 | |
| 产品简述 | This RGD-containing sequence is integrin-binding site. RGD peptides are found in both extracellular matrix (ECM) (e.g., collagen, osteopontin, fibronectin, and vitronectin) and non-ECM proteins (e.g., disintegrins). RGD-containing peptides are recognized by several integrins. This peptide targets both alphavbeta3 and alpha5beta1 integrins. Interaction of the RGDN sequence with endothelial alpha5beta1 integrin causes endothelin-mediated arteriolar vasoconstriction. This peptide influences the IkappaB kinase (IKK)/nuclear factor-kappaB (NF-kappaB) activation. It also controls the cardiac contractile function. |