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名称 RGDS
CAS No. 91037-65-9
目录号 ONP10806
规格 mg/g
纯度 ≥98%
价格 更多在线询价
贮存 -20°C
分子量 433.4
序列结构 H-Arg-Gly-Asp-Ser-OH
库存
产品简述 The RGD peptide is the binding motif of fibronectin to cell adhesion molecules. RGD peptide acts as an inhibitor of integrin-ligand interactions and can induce apoptosis in the absence of signals and integrin-mediated cell clustering. The RGDS sequence was found initially to promote the attachment of rat kidney fibroblasts to fibronectin. The free RGDS peptide inhibits attachment of cells to fibronectin-coated substrates. The RGDS sequence is also a target for infectious agents (Treponema's syphilis, Mycobacterium's tuberculosis). RGDS can also block fibrinogen-induced aggregation of intact erythrocytes and specific binding of fibrinogen to erythrocyte membranes.