β-amyloid (1-16) - Ontores  

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β-amyloid (1-16)

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名称 β-amyloid (1-16)
CAS No. 131580-10-4
目录号 ONP10824
规格 mg/g
纯度 ≥98%
价格 更多在线询价
贮存 -20°C
分子量 1955.02
序列结构 H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-OH
库存
产品简述 Proteins interactions with reactive oxygen agents may result in covalent modifications of amino acid residues in proteins, formation of protein-protein cross-linkages and oxidation of the protein backbone resulting in protein fragmentation. Oxidation targets for Beta-amyloid (1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aß in senile plaque of Alzheimer’s disease with Beta-amyloid (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of Aß and free radical damage.