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Davalintide

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名称 Davalintide
CAS No. 863919-85-1
目录号 ONP20128
规格 mg/g/kg
纯度 ≥98%
价格 更多在线询价
贮存 -20°C
分子量 3624.077
序列结构 H-Lys-Cys(1)-Asn-Thr-Ala-Thr-Cys(1)-Val-Leu-Gly-Arg-Leu-Ser-Gln-Glu-Leu-His-Arg-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2
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产品简述 A second-generation, 32-amino acid peptide analogue of human amylin with antihyperglycemic activity. By mimicking amylin, davalintide, which has a half-life similar to amylin, slows gastric emptying, inhibits digestive secretions (gastric acid, pancreatic enzymes, and bile), reduces glucagon secretion, and increases satiety. These actions result in a decrease in blood glucose levels. Furthermore, davalintide exhibits high affinity binding to amylin, calcitonin and calcitonin-related peptide receptors. Compared to amylin, davalintide shows a prolonged duration of action due to its slowed receptor dissociation.