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Colivelin
添加购物车| 名称 | Colivelin |
|---|---|
| CAS No. | 867021-83-8 |
| 目录号 | ONP10672 |
| 规格 | mg/g |
| 纯度 | ≥98% |
| 价格 | 更多在线询价 |
| 贮存 | -20°C |
| 分子量 | 2645.1 |
| 序列结构 | H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH |
| 库存 | |
| 产品简述 | Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN). Colivelin is constructed as activity-dependent neurotrophic factor (ADNF) C-terminally fused to AGA-(C8R) HNG17, which is a potent HN derivative. Cell death induced by overexpressed familial Alzheimer's disease (FAD)-causative genes and beta-amyloid (1-43) can be completely suppressed by colivelin. Colivelin administered intraperitoneally suppresses memory impairment and may serve as a novel drug candidate to treat Alzheimer's disease. |