关注我们
Gly-Arg-Gly-Asp-Asn-Pro
添加购物车| 名称 | Gly-Arg-Gly-Asp-Asn-Pro |
|---|---|
| CAS No. | 114681-65-1 |
| 目录号 | ONP10535 |
| 规格 | mg/g |
| 纯度 | ≥98% |
| 价格 | 更多在线询价 |
| 贮存 | -20°C |
| 分子量 | 614.6 |
| 序列结构 | H-GLY-ARG-GLY-ASP-ASN-PRO-OH |
| 库存 | |
| 产品简述 | G-R-G-D-N-P is a superior inhibitor of cell attachment to fibronectin and a weak inhibitor of cell attacment to vitronectin. It also inhibits binding of fibrinogen, fibronectin, vitronectin and von Willebrand factor to platelets and resists to carboxypeptidases. G-R-G-D-N-P induces apoptosis in various cell types and cell lines at 1mM by a mechanism involving cellular uptake and possible direct stimulation of procaspase-3 autoprocessing. It contains the motif RGD (Arg-Gly-Asp) which is found in many integrin ligands. G-R-G-D-N-P inhibits cell adhesion to fibronectin 80-90% at 1 mM. |