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Gamma-2-MSH (41-58), amide
添加购物车| 名称 | Gamma-2-MSH (41-58), amide |
|---|---|
| CAS No. | |
| 目录号 | ONP10547 |
| 规格 | mg/g |
| 纯度 | ≥98% |
| 价格 | 更多在线询价 |
| 贮存 | -20°C |
| 分子量 | 1570.78 |
| 序列结构 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-OH |
| 库存 | |
| 产品简述 | Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cells. Most of the cells responding to 3-MSH express more than one pituitary hormone mRNA. The effect of 3-MSH is blocked by SHU9119, a MC3R and MC4R antagonist, in only 50% of the responsive cells, suggesting that in half of these cells the mediating receptor is not the MC3R. Low picomolar doses of 3-MSH increase [Ca2+]i in the growth hormone (GH)- and prolactin (PRL)-secreting GH3 cell line. |