Bradykinin (1-5) - Ontores  

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Bradykinin (1-5)

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名称 Bradykinin (1-5)
CAS No. 23815-89-6
目录号 ONP10579
规格 mg/g
纯度 ≥98%
价格 更多在线询价
贮存 -20°C
分子量 572.66
序列结构 H-ARG-PRO-PRO-GLY-PHE-OH
库存
产品简述 The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. Bradykinin (1-5) may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for certain biological activities. BK 1-5 is the smallest peptide that can inhibit α-thrombin-induced platelet aggregation and secretion and calcium mobilization. Bradykinin (1-5) also prevents α-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins.